thoc3 THO complex 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: thoc3provided by ZNC
Official Full Name: THO complex 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040808-14
See related: Ensembl:ENSDARG00000056517 AllianceGenome:ZFIN:ZDB-GENE-040808-14
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:100815
Summary: Predicted to be involved in mRNA export from nucleus. Predicted to be part of THO complex part of transcription export complex. Orthologous to human THOC3 (THO complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (25505474..25510955)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (25208229..25213710)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in mRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mRNA export from nucleus	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of THO complex part of transcription export complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: THO complex subunit 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003758.1 → NP_001003758.1 THO complex subunit 3

See identical proteins and their annotated locations for NP_001003758.1

Status: PROVISIONAL

Source sequence(s)

BC079495

UniProtKB/TrEMBL

A7YYD8, F6NRC9, Q6AXK9

Related

ENSDARP00000073472.4, ENSDART00000079016.5

Conserved Domains (3) summary

COG2319
Location:15 → 300

WD40; WD40 repeat [General function prediction only]

cd00200
Location:15 → 261

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:30 → 68

7WD40; WD40 repeat [structural motif]