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neu3.2 sialidase 3 (membrane sialidase), tandem duplicate 2 [ Danio rerio (zebrafish) ]

Gene ID: 445250, updated on 9-Dec-2024

Summary

Official Symbol
neu3.2provided by ZNC
Official Full Name
sialidase 3 (membrane sialidase), tandem duplicate 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-262
See related
Ensembl:ENSDARG00000010047 AllianceGenome:ZFIN:ZDB-GENE-040801-262
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:6912336; zgc:100806
Summary
Enables exo-alpha-sialidase activity. Predicted to be involved in ganglioside catabolic process and oligosaccharide catabolic process. Predicted to act upstream of or within lipid catabolic process. Located in cytosol. Is expressed in several structures, including gill; heart; integument; liver; and pleuroperitoneal region. Orthologous to human NEU3 (neuraminidase 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See neu3.2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (21796710..21799292)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (21760074..21762656)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene X-ray radiation resistance associated 1 Neighboring gene sialidase 3 (membrane sialidase), tandem duplicate 1 Neighboring gene sialidase 3 (membrane sialidase), tandem duplicate 3 Neighboring gene sialidase 3 (membrane sialidase), tandem duplicate 4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables exo-alpha-sialidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables exo-alpha-sialidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables exo-alpha-sialidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in ganglioside catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in oligosaccharide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
sialidase-3.2
Names
sialidase 3, tandem duplicate 2
sialidase 3.2
NP_001003644.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003644.2NP_001003644.2  sialidase-3.2

    See identical proteins and their annotated locations for NP_001003644.2

    Status: PROVISIONAL

    Source sequence(s)
    BC096984
    UniProtKB/TrEMBL
    Q4V9A4
    Related
    ENSDARP00000017916.8, ENSDART00000003518.9
    Conserved Domains (2) summary
    cd15482
    Location:15370
    Sialidase_non-viral; Non-viral sialidases
    pfam13088
    Location:44348
    BNR_2; BNR repeat-like domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    21796710..21799292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395090.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    485..2218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)