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cks1b CDC28 protein kinase regulatory subunit 1B [ Danio rerio (zebrafish) ]

Gene ID: 445199, updated on 4-Jan-2025

Summary

Official Symbol
cks1bprovided by ZNC
Official Full Name
CDC28 protein kinase regulatory subunit 1Bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-112
See related
Ensembl:ENSDARG00000007971 AllianceGenome:ZFIN:ZDB-GENE-040801-112
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101026
Summary
Predicted to enable several functions, including cyclin-dependent protein serine/threonine kinase activator activity; histone binding activity; and ubiquitin binding activity. Predicted to be involved in regulation of mitotic cell cycle. Predicted to be part of SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Orthologous to human CKS1B (CDC28 protein kinase regulatory subunit 1B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See cks1b in Genome Data Viewer
Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (7835025..7838232)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (7916100..7919307)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene aquaporin 10b Neighboring gene small nucleolar RNA SNORA13 Neighboring gene zinc finger protein 687b Neighboring gene nuclear GTPase, germinal center associated, tandem duplicate 2 Neighboring gene nuclear GTPase, germinal center associated, tandem duplicate 1 Neighboring gene nuclear GTPase, germinal center associated, tandem duplicate 3

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cyclin-dependent kinases regulatory subunit 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003593.3NP_001003593.1  cyclin-dependent kinases regulatory subunit 1

    See identical proteins and their annotated locations for NP_001003593.1

    Status: VALIDATED

    Source sequence(s)
    BM037555, CR628394, EH540885
    UniProtKB/TrEMBL
    A0A8M1N1L7, Q6DEL8
    Related
    ENSDARP00000003357.4, ENSDART00000026276.6
    Conserved Domains (1) summary
    pfam01111
    Location:873
    CKS; Cyclin-dependent kinase regulatory subunit

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    7835025..7838232
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)