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dnajb1a DnaJ heat shock protein family (Hsp40) member B1a [ Danio rerio (zebrafish) ]

Gene ID: 445177, updated on 9-Dec-2024

Summary

Official Symbol
dnajb1aprovided by ZNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member B1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-90
See related
Ensembl:ENSDARG00000099383 AllianceGenome:ZFIN:ZDB-GENE-040801-90
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hspf1; dnajb1; zf-Hsp40; zgc:101068
Summary
Predicted to enable Hsp70 protein binding activity; transcription corepressor activity; and unfolded protein binding activity. Acts upstream of or within lens development in camera-type eye. Predicted to be active in cytosol. Orthologous to human DNAJB1 (DnaJ heat shock protein family (Hsp40) member B1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See dnajb1a in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (49150813..49163648, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (45005411..45018237, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 35-12 Neighboring gene GIPC PDZ domain containing family, member 1 Neighboring gene uncharacterized LOC137490149 Neighboring gene uncharacterized LOC137490150 Neighboring gene uncharacterized LOC137490774

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables Hsp70 protein binding  
enables transcription corepressor activity  
enables unfolded protein binding  
enables unfolded protein binding  
Component Evidence Code Pubs
is_active_in cytosol  

General protein information

Preferred Names
dnaJ homolog subfamily B member 1a
Names
DnaJ (Hsp40) homolog, subfamily B, member 1
DnaJ (Hsp40) homolog, subfamily B, member 1a
heat shock 40kD protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003571.1 → NP_001003571.1  dnaJ homolog subfamily B member 1a

    See identical proteins and their annotated locations for NP_001003571.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077119
    UniProtKB/TrEMBL
    Q6DEJ4
    Related
    ENSDARP00000141952.1, ENSDART00000166146.2
    Conserved Domains (3) summary
    cd10747
    Location:157 → 321
    DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
    COG0484
    Location:1 → 335
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    pfam00226
    Location:4 → 65
    DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    49150813..49163648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068216646.1 → XP_068072747.1  dnaJ homolog subfamily B member 1a isoform X1

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