KLRD1 killer cell lectin-like receptor subfamily D, member 1 [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: KLRD1
Gene description: killer cell lectin-like receptor subfamily D, member 1
See related: BGD:BT27451; EnsemblRapid:ENSBTAG00070027969
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: CD94; CD94-1
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	5	NC_037332.1 (99623592..99660578, complement)

Chromosome 5 - NC_037332.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These findings suggest that the CD94/NKG2A heterodimers in cattle, in contrast to other species, are binding several different ligands.
Title: Complexity in the cattle CD94/NKG2 gene families.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables (1->3)-beta-D-glucan binding	IEA Inferred from Electronic Annotation more info	PubMed
enables pattern recognition receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to molecule of fungal origin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in detection of fungus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in detection of molecule of fungal origin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phagocytosis, recognition	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytokine production involved in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of killing of cells of another organism	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of lymphocyte activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of natural killer cell mediated cytotoxicity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of phagocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of wound healing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in stimulatory C-type lectin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info	PubMed
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: natural killer cells antigen CD94

Names: killer cell lectin-like receptor family D member 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002890.1 → NP_001002890.1 natural killer cells antigen CD94

See identical proteins and their annotated locations for NP_001002890.1

Status: PROVISIONAL

Source sequence(s)

AF422180

UniProtKB/Swiss-Prot

A3R3C2, A3R3C3, A3R3C4, Q863H3

Related

ENSBTAP00070038271.1, ENSBTAT00070063755.1

Conserved Domains (1) summary

cd03593
Location:72 → 187

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

Range

99623592..99660578 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_059886145.1 → XP_059742128.1 natural killer cells antigen CD94 isoform X1
XM_024991426.2 → XP_024847194.1 natural killer cells antigen CD94 isoform X1

Conserved Domains (1) summary

cd03593
Location:95 → 218

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
XM_059886146.1 → XP_059742129.1 natural killer cells antigen CD94 isoform X2

UniProtKB/TrEMBL

A0A2Z2AR18
XM_015471264.3 → XP_015326750.1 natural killer cells antigen CD94 isoform X2

UniProtKB/TrEMBL

A0A2Z2AR18

Conserved Domains (1) summary

cd03593
Location:72 → 177

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)