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tio - tiptop

Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including Malpighian tubule stellate cell differentiation; epidermis morphogenesis; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in embryonic specialized Malpighian tubule cell; eye disc anterior to the morphogenetic furrow; and imaginal disc. Orthologous to human TSHZ1 (teashirt zinc finger homeobox 1); TSHZ2 (teashirt zinc finger homeobox 2); and TSHZ3 (teashirt zinc finger homeobox 3). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa