Pgm1 Phosphoglucose mutase 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Pgm1provided by FlyBase
Official Full Name: Phosphoglucose mutase 1provided by FlyBase
Primary source: FLYBASE:FBgn0003076
Locus tag: Dmel_CG5165
See related: AllianceGenome:FB:FBgn0003076
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG5165; Dmel\CG5165; dPgm; pgm; Pgm; PGM; Pgm-1; PGM-1; PGM1
Summary: Enables phosphoglucomutase activity. Involved in several processes, including glucose 1-phosphate metabolic process; glycogen metabolic process; and glycolytic process through glucose-1-phosphate. Predicted to be active in cytosol. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Orthologous to human PGM1 (phosphoglucomutase 1) and PGM5 (phosphoglucomutase 5). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (16126018..16128531, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (16119118..16121631, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables phosphoglucomutase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphoglucomutase activity	IDA Inferred from Direct Assay more info	PubMed
enables phosphoglucomutase activity	IEA Inferred from Electronic Annotation more info
enables phosphoglucomutase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables phosphoglucomutase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in galactose catabolic process via UDP-galactose	ISS Inferred from Sequence or Structural Similarity more info
involved_in glucose 1-phosphate metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in glucose 6-phosphate metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in glycogen biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glycogen catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glycolytic process through glucose-1-phosphate	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

Names: CG5165-PA; Pgm1-PA; phosphoglucomutase; phosphogluconate mutase; phosphoglucose mutase

NP_524675.1

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The following sections contain reference sequences that belong to a specific genome build. Explain