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jbug jitterbug [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43997, updated on 18-Sep-2024

Summary

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Official Symbol
jbugprovided by FlyBase
Official Full Name
jitterbugprovided by FlyBase
Primary source
FLYBASE:FBgn0028371
Locus tag
Dmel_CG30092
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AAF46896; CG11605; CG13525; CG30092; CG3550; Dmel\CG30092; Jbug
Orthologs
all
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Genomic context

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See jbug in Genome Data Viewer
Location:
59A3-59A3; 2-101 cM
Exon count:
20
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22717321..22740459, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18604826..18627964, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43735 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR30267 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development. Chung S, et al. Genetics, 2021 Oct 2. PMID 34173831, Free PMC Article
  2. Jitterbug/Filamin and Myosin-II form a complex in tendon cells required to maintain epithelial shape and polarity during musculoskeletal system development. Manieu C, et al. Mech Dev, 2018 Dec. PMID 30213743
  3. Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in axon guidance in Drosophila. Oliva C, et al. Dev Neurobiol, 2015 Sep. PMID 25652545
  4. Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila. Hekmat-Scafe DS, et al. J Neurosci, 2006 Aug 30. PMID 16943550, Free PMC Article
  5. Intertissue mechanical stress affects Frizzled-mediated planar cell polarity in the Drosophila notum epidermis. Olguín P, et al. Curr Biol, 2011 Feb 8. PMID 21276726, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development.
    Title: Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
jitterbug
Names
CG30092-PC
CG30092-PF
CG30092-PG
CG30092-PH
CG30092-PI
CG30092-PJ
CG30092-PK
CG30092-PL
CG30092-PM
CG30092-PN
filamin
jbug-PC
jbug-PF
jbug-PG
jbug-PH
jbug-PI
jbug-PJ
jbug-PK
jbug-PL
jbug-PM
jbug-PN

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22717321..22740459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274210.1 → NP_001261139.1  jitterbug, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261139.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KEX6
    Conserved Domains (5) summary
    smart00557
    Location:2734 → 2828
    IG_FLMN; Filamin-type immunoglobulin domains
    cd00014
    Location:60 → 165
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00307
    Location:172 → 269
    CH; Calponin homology (CH) domain
    pfam00630
    Location:2731 → 2821
    Filamin; Filamin/ABP280 repeat
    pfam17069
    Location:639 → 918
    RSRP; Arginine/Serine-Rich protein 1

  2. NM_001274211.1 → NP_001261140.1  jitterbug, isoform N [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261140.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KFF9
    Conserved Domains (4) summary
    smart00557
    Location:2850 → 2944
    IG_FLMN; Filamin-type immunoglobulin domains
    cd00014
    Location:60 → 165
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00307
    Location:172 → 269
    CH; Calponin homology (CH) domain
    pfam00630
    Location:2847 → 2937
    Filamin; Filamin/ABP280 repeat

  3. NM_166546.3 → NP_726234.3  jitterbug, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726234.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W205
    Conserved Domains (4) summary
    smart00557
    Location:2850 → 2944
    IG_FLMN; Filamin-type immunoglobulin domains
    cd00014
    Location:60 → 165
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00307
    Location:172 → 269
    CH; Calponin homology (CH) domain
    pfam00630
    Location:2847 → 2937
    Filamin; Filamin/ABP280 repeat

  4. NM_001169787.2 → NP_001163258.1  jitterbug, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163258.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JGS7
    Conserved Domains (2) summary
    smart00557
    Location:1647 → 1741
    IG_FLMN; Filamin-type immunoglobulin domains
    pfam00630
    Location:1644 → 1734
    Filamin; Filamin/ABP280 repeat

  5. NM_166547.2 → NP_726235.2  jitterbug, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726235.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q058S6, Q9W204
    Conserved Domains (4) summary
    smart00557
    Location:1480 → 1569
    IG_FLMN; Filamin-type immunoglobulin domains
    cd00014
    Location:60 → 165
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00307
    Location:172 → 269
    CH; Calponin homology (CH) domain
    pfam00630
    Location:1477 → 1563
    Filamin; Filamin/ABP280 repeat

  6. NM_001169786.2 → NP_001163257.1  jitterbug, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163257.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6AWQ7, Q8MME5
    Conserved Domains (2) summary
    smart00557
    Location:277 → 366
    IG_FLMN; Filamin-type immunoglobulin domains
    pfam00630
    Location:274 → 360
    Filamin; Filamin/ABP280 repeat

  7. NM_166550.3 → NP_726238.1  jitterbug, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726238.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6AWQ7, Q8MME5
    Related
    FBpp0071830
    Conserved Domains (2) summary
    smart00557
    Location:277 → 366
    IG_FLMN; Filamin-type immunoglobulin domains
    pfam00630
    Location:274 → 360
    Filamin; Filamin/ABP280 repeat

  8. NM_001169789.2 → NP_001163260.1  jitterbug, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163260.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6AWQ7, Q8MME5
    Conserved Domains (2) summary
    smart00557
    Location:277 → 366
    IG_FLMN; Filamin-type immunoglobulin domains
    pfam00630
    Location:274 → 360
    Filamin; Filamin/ABP280 repeat

  9. NM_001169785.2 → NP_001163256.1  jitterbug, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163256.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6AWQ7, Q8MME5
    Conserved Domains (2) summary
    smart00557
    Location:277 → 366
    IG_FLMN; Filamin-type immunoglobulin domains
    pfam00630
    Location:274 → 360
    Filamin; Filamin/ABP280 repeat

  10. NM_001169788.2 → NP_001163259.1  jitterbug, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163259.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6AWQ7, Q8MME5
    Conserved Domains (2) summary
    smart00557
    Location:277 → 366
    IG_FLMN; Filamin-type immunoglobulin domains
    pfam00630
    Location:274 → 360
    Filamin; Filamin/ABP280 repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KEX6 A0A0B4KEX6
A0A0B4KFF9 A0A0B4KFF9
E1JGS7 E1JGS7
Q8MME5 Q8MME5
Q95U66 Q95U66
Q961W2 Q961W2
Q9W204 Q9W204
Q9W205 Q9W205

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