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sif - still life

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including actin cytoskeleton organization; regulation of plasma membrane bounded cell projection organization; and visual perception. Located in synapse. Is expressed in several structures, including ganglia; organism subdivision; presumptive embryonic/larval central nervous system; spermatozoon; and synaptic neuropil domain. Used to study cataract 48 and neurodevelopmental disorder with language delay and seizures. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with language delay and seizures. Orthologous to human TIAM1 (TIAM Rac1 associated GEF 1) and TIAM2 (TIAM Rac1 associated GEF 2). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to sif

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Species Gene Architecture aa