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Crk - Crk oncogene

Enables receptor tyrosine kinase binding activity. Involved in several processes, including border follicle cell migration; imaginal disc fusion, thorax closure; and positive regulation of JNK cascade. Predicted to be active in cytoplasm. Is expressed in several structures, including cephalic furrow; gut section; larval ventral nerve cord; somatic mesoderm; and visceral muscle cell. Human ortholog(s) of this gene implicated in chronic myeloid leukemia. Orthologous to human CRKL (CRK like proto-oncogene, adaptor protein) and CRK (CRK proto-oncogene, adaptor protein). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa