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pygo - pygopus

Enables methylated histone binding activity and transcription coactivator activity. Involved in several processes, including instar larval or pupal development; positive regulation of transcription by RNA polymerase II; and segment polarity determination. Located in nucleus. Part of beta-catenin-TCF complex. Is expressed in cardioblast and organism. Used to study heart conduction disease. Orthologous to human PYGO1 (pygopus family PHD finger 1) and PYGO2 (pygopus family PHD finger 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa