Gcn2 - Gcn2
Enables eukaryotic translation initiation factor 2alpha kinase activity. Involved in positive regulation of cell size and regulation of translational initiation. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including amnioproctodeal invagination; embryonic/larval midgut primordium; epithelial furrow; ganglia; and gut section. Human ortholog(s) of this gene implicated in pulmonary venoocclusive disease 2. Orthologous to human EIF2AK4 (eukaryotic translation initiation factor 2 alpha kinase 4). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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