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denr density-regulated protein [ Danio rerio (zebrafish) ]

Gene ID: 436970, updated on 4-Jan-2025

Summary

Official Symbol
denrprovided by ZNC
Official Full Name
density-regulated proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-450
See related
Ensembl:ENSDARG00000037229 AllianceGenome:ZFIN:ZDB-GENE-040718-450
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92629; im:6891640; zgc:113309
Summary
Predicted to enable translation initiation factor activity. Predicted to be involved in formation of translation preinitiation complex and translation reinitiation. Predicted to act upstream of or within translational initiation. Is expressed in midbrain; myotome; optic vesicle; and retina. Orthologous to human DENR (density regulated re-initiation and release factor). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information
Annotation category: suggests misassembly
Annotation category: partial on reference assembly
Orthologs
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Genomic context

See denr in Genome Data Viewer
Location:
chromosome: 10
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (44402825..44443349)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (44601282..44643202)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene lysine methyltransferase 5Aa Neighboring gene small nuclear ribonucleoprotein 35 (U11/U12) Neighboring gene CAP-GLY domain containing linker protein 1b Neighboring gene Rab interacting lysosomal protein-like 1 Neighboring gene CAP-Gly domain-containing linker protein 1 Neighboring gene hydroxycarboxylic acid receptor 1-2 Neighboring gene hydroxycarboxylic acid receptor 1-1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in formation of translation preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation reinitiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within translational initiation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
density-regulated protein
Names
DRP

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002697.2NP_001002697.1  density-regulated protein

    See identical proteins and their annotated locations for NP_001002697.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095896
    UniProtKB/Swiss-Prot
    Q6DH65
    Related
    ENSDARP00000149057.1, ENSDART00000181517.1
    Conserved Domains (1) summary
    cl00229
    Location:26203
    eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    44402825..44443349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)