qless qless [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: qlessprovided by FlyBase
Official Full Name: qlessprovided by FlyBase
Primary source: FLYBASE:FBgn0051005
Locus tag: Dmel_CG31005
See related: AllianceGenome:FB:FBgn0051005
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.422; CG15565; CG31005; CG3684; Dmel\CG31005; Qless
Summary: Predicted to enable prenyltransferase activity. Predicted to contribute to all-trans-decaprenyl-diphosphate synthase activity. Involved in several processes, including negative regulation of apoptotic process; neuroblast development; and response to mitochondrial depolarisation. Predicted to be part of heterotetrameric polyprenyl diphosphate synthase complex. Predicted to be active in mitochondrion. Is expressed in several structures, including embryonic dorsal epidermis; embryonic esophagus; embryonic head epidermis; embryonic hypopharynx; and embryonic ventral epidermis. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Orthologous to human PDSS1 (decaprenyl diphosphate synthase subunit 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (31236035..31252608, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (27061757..27078330, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to all-trans-decaprenyl-diphosphate synthase activity	ISS Inferred from Sequence or Structural Similarity more info
enables prenyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables prenyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in isoprenoid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in isoprenoid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in isoprenoid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuroblast development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to mitochondrial depolarisation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ubiquinone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of heterotetrameric polyprenyl diphosphate synthase complex	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of polyprenyl diphosphate synthase complex	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain