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eci2 enoyl-CoA delta isomerase 2 [ Danio rerio (zebrafish) ]

Gene ID: 436918, updated on 4-Jan-2025

Summary

Official Symbol
eci2provided by ZNC
Official Full Name
enoyl-CoA delta isomerase 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-392
See related
Ensembl:ENSDARG00000102412 AllianceGenome:ZFIN:ZDB-GENE-040718-392
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
PECI; fd61c12; zgc:92030; wu:fd61c12; zgc:175023
Summary
Predicted to enable delta(3)-delta(2)-enoyl-CoA isomerase activity and fatty-acyl-CoA binding activity. Orthologous to human ECI2 (enoyl-CoA delta isomerase 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See eci2 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (2956352..2972040)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (2957507..2973296)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137489201 Neighboring gene uncharacterized LOC103909736 Neighboring gene tubulin, beta 6 class V Neighboring gene cell death inducing DFFA like effector a Neighboring gene uncharacterized LOC110438346 Neighboring gene succinyl-CoA:glutarate-CoA transferase Neighboring gene inhibin subunit beta Aa

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General protein information

Preferred Names
enoyl-CoA delta isomerase 2
NP_001002645.3
XP_021325811.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002645.3NP_001002645.3  enoyl-CoA delta isomerase 2

    Status: VALIDATED

    Source sequence(s)
    FP236475
    UniProtKB/TrEMBL
    A0A8M1N0S4
    Related
    ENSDARP00000130260.1, ENSDART00000170835.2
    Conserved Domains (2) summary
    cd00435
    Location:39123
    ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    cl23717
    Location:140387
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    2956352..2972040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470136.1XP_021325811.1  enoyl-CoA delta isomerase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M1N0S4, A0A8M9P5U3
    Conserved Domains (2) summary
    cd00435
    Location:488
    ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    cl23717
    Location:105352
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...