U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

lemd1 LEM domain containing 1 [ Danio rerio (zebrafish) ]

Gene ID: 436879, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
lemd1provided by ZNC
Official Full Name
LEM domain containing 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-350
See related
Ensembl:ENSDARG00000040161 AllianceGenome:ZFIN:ZDB-GENE-040718-350
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92287
Summary
Predicted to enable DNA binding activity. Predicted to be located in membrane and nuclear envelope. Is expressed in hindbrain; musculature system; myotome; and pectoral fin musculature. Orthologous to human LEMD1 (LEM domain containing 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See lemd1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (18032569..18057912, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (18106189..18131607, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene peptidase M20 domain containing 1, tandem duplicate 2 Neighboring gene peptidase M20 domain containing 1, tandem duplicate 1 Neighboring gene microRNA 135c-2 Neighboring gene major facilitator superfamily domain containing 4Ab

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
LEM domain-containing protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002606.1 → NP_001002606.1  LEM domain-containing protein 1

    See identical proteins and their annotated locations for NP_001002606.1

    Status: PREDICTED

    Source sequence(s)
    BC075986
    UniProtKB/TrEMBL
    A0A8M1N0S8, A0A8M6YV85, Q6DHI6
    Related
    ENSDARP00000058741.5, ENSDART00000058742.6
    Conserved Domains (2) summary
    cd12940
    Location:75 → 116
    LEM_LAP2_LEMD1; LEM (Lap2/Emerin/Man1) domain found in lamina-associated polypeptide 2 (LAP2), LEM domain-containing protein 1 (LEMP-1) and similar proteins
    pfam08198
    Location:2 → 49
    Thymopoietin; Thymopoietin protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    18032569..18057912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017353543.3 → XP_017209032.1  LEM domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8M2B8V4, A0A8M6YXP2
    Related
    ENSDARP00000142311.1, ENSDART00000173068.2

  2. XM_068216729.1 → XP_068072830.1  LEM domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B8V4, A0A8M9PKP3

  3. XM_021469781.2 → XP_021325456.1  LEM domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8M9PT08, A0A8M9PWF4
    Conserved Domains (2) summary
    cd12940
    Location:75 → 116
    LEM_LAP2_LEMD1; LEM (Lap2/Emerin/Man1) domain found in lamina-associated polypeptide 2 (LAP2), LEM domain-containing protein 1 (LEMP-1) and similar proteins
    pfam08198
    Location:3 → 49
    Thymopoietin; Thymopoietin protein

  4. XM_009296725.4 → XP_009295000.1  LEM domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M3AV65, A0A8M9PWF4
    Conserved Domains (2) summary
    cd12940
    Location:75 → 116
    LEM_LAP2_LEMD1; LEM (Lap2/Emerin/Man1) domain found in lamina-associated polypeptide 2 (LAP2), LEM domain-containing protein 1 (LEMP-1) and similar proteins
    pfam08198
    Location:2 → 49
    Thymopoietin; Thymopoietin protein

  5. XM_005162055.5 → XP_005162112.1  LEM domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B903, A0A8M6YVU6
    Conserved Domains (2) summary
    cd12940
    Location:75 → 116
    LEM_LAP2_LEMD1; LEM (Lap2/Emerin/Man1) domain found in lamina-associated polypeptide 2 (LAP2), LEM domain-containing protein 1 (LEMP-1) and similar proteins
    pfam08198
    Location:2 → 49
    Thymopoietin; Thymopoietin protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.