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gcshb glycine cleavage system protein H (aminomethyl carrier), b [ Danio rerio (zebrafish) ]

Gene ID: 436852, updated on 4-Jan-2025

Summary

Official Symbol
gcshbprovided by ZNC
Official Full Name
glycine cleavage system protein H (aminomethyl carrier), bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-319
See related
Ensembl:ENSDARG00000105187 AllianceGenome:ZFIN:ZDB-GENE-040718-319
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92732; wu:fd56h06; zgc:110557
Summary
Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be part of glycine cleavage complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome. Orthologous to human GCSH (glycine cleavage system protein H). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See gcshb in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (67451169..67463021)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (67227817..67239669)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene nuclear factor of activated T cells 5b Neighboring gene lysyl-tRNA synthetase 1 Neighboring gene small nucleolar RNA MBII-202 Neighboring gene small nucleolar RNA MBII-202 Neighboring gene ribosomal protein L13

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in glycine decarboxylation via glycine cleavage system IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within glycine decarboxylation via glycine cleavage system IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of glycine cleavage complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of glycine cleavage complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glycine cleavage system protein H (aminomethyl carrier), b
Names
mitochondrial glycine cleavage system H protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002579.1NP_001002579.1  glycine cleavage system protein H (aminomethyl carrier), b

    See identical proteins and their annotated locations for NP_001002579.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076212
    UniProtKB/TrEMBL
    A0A0R4IGT7, B2GTH2, Q6DGX4
    Related
    ENSDARP00000134597.1, ENSDART00000163840.2
    Conserved Domains (1) summary
    PRK01202
    Location:52171
    PRK01202; glycine cleavage system protein H; Provisional

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    67451169..67463021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)