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aqp12 aquaporin 12 [ Danio rerio (zebrafish) ]

Gene ID: 436844, updated on 9-Dec-2024

Summary

Official Symbol
aqp12provided by ZNC
Official Full Name
aquaporin 12provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-310
See related
Ensembl:ENSDARG00000043279 AllianceGenome:ZFIN:ZDB-GENE-040718-310
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92747; wu:fb60e09; zgc:152755
Summary
Predicted to enable channel activity. Acts upstream of or within cellular response to estrogen stimulus. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including eye; gill; integument; liver; and pleuroperitoneal region. Orthologous to human AQP12A (aquaporin 12A) and AQP12B (aquaporin 12B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See aqp12 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (2874831..2886946, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (2858565..2870680, complement)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene si:dkey-20i20.2 Neighboring gene zgc:174224 Neighboring gene transfer RNA methionine (anticodon CAU) Neighboring gene transfer RNA isoleucine (anticodon AAU)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC152755

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to estrogen stimulus IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045862.2NP_001039327.1  aquaporin 12

    See identical proteins and their annotated locations for NP_001039327.1

    Status: VALIDATED

    Source sequence(s)
    BC076225, BC121752, BX324210
    UniProtKB/TrEMBL
    A0A8M1NAS4, Q0IIQ6
    Related
    ENSDARP00000063532.3, ENSDART00000063533.4
    Conserved Domains (1) summary
    cl00200
    Location:41243
    MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    2874831..2886946 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)