n6amt1 N-6 adenine-specific DNA methyltransferase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: n6amt1provided by ZNC
Official Full Name: N-6 adenine-specific DNA methyltransferase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-206
See related: Ensembl:ENSDARG00000115421 AllianceGenome:ZFIN:ZDB-GENE-040718-206
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92834
Summary: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity and protein methyltransferase activity. Predicted to act upstream of or within methylation. Predicted to be part of eRF1 methyltransferase complex. Orthologous to human N6AMT1 (N-6 adenine-specific DNA methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (961607..970952)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (966428..975876)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables S-adenosylmethionine-dependent methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables protein methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables site-specific DNA-methyltransferase (adenine-specific) activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of eRF1 methyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: methyltransferase N6AMT1

Names: N-6 adenine-specific DNA methyltransferase 1 (putative)

NP_001002502.1

EC 2.1.1.72

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002502.1 → NP_001002502.1 methyltransferase N6AMT1

See identical proteins and their annotated locations for NP_001002502.1

Status: PROVISIONAL

Source sequence(s)

BC076297

UniProtKB/TrEMBL

Q6DGP3

Related

ENSDARP00000157105.1, ENSDART00000184660.1

Conserved Domains (2) summary

COG2890
Location:16 → 213

HemK; Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]

cl17173
Location:17 → 211

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...