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cindr - CIN85 and CD2AP related

Enables GTPase activating protein binding activity; SH3 domain binding activity; and cell adhesion molecule binding activity. Involved in several processes, including adherens junction assembly; border follicle cell migration; and positive regulation of receptor-mediated endocytosis. Located in several cellular components, including cleavage furrow; fusome; and midbody. Is active in apical cortex; neuromuscular junction; and presynapse. Is expressed in several structures, including adult head; adult head sensillum; germline cell; imaginal disc; and pigment cell. Used to study nephrotic syndrome and tauopathy. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 3; and immunodeficiency 61. Orthologous to human CD2AP (CD2 associated protein) and SH3KBP1 (SH3 domain containing kinase binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to cindr

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Species Gene Architecture aa