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CG9747 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43591, updated on 9-Dec-2024

Summary

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Official Symbol
CG9747provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039754
Locus tag
Dmel_CG9747
See related
AllianceGenome:FB:FBgn0039754
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel MPSE; Dmel\CG9747
Summary
Predicted to enable iron ion binding activity and stearoyl-CoA 9-desaturase activity. Predicted to be involved in unsaturated fatty acid biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult head; embryonic dorsal apodeme; embryonic dorsal epidermis; embryonic epipharynx; and gut section. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG9747 in Genome Data Viewer
Location:
99E1-99E2; 3-100 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30185423..30191252, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26011145..26016974, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Blocked early in transport 5 Neighboring gene long non-coding RNA:CR44262 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamic reprogramming of chromatin accessibility during Drosophila embryo development. Thomas S, et al. Genome Biol, 2011. PMID 21569360, Free PMC Article
  2. Molecular genetics and evolution of pheromone biosynthesis in Lepidoptera. Roelofs WL, et al. Proc Natl Acad Sci U S A, 2003 Aug 5. PMID 12876197, Free PMC Article
  3. Molecular Basis for Cephalic Mechanosensitivity of Drosophila Larvae. Zhang Z, et al. Neurosci Bull, 2020 Sep. PMID 32761438, Free PMC Article
  4. DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner. Fortuna TR, et al. Acta Neuropathol, 2021 Sep. PMID 34061233, Free PMC Article
  5. Mosaic genetic screen for suppressors of the de2f1 mutant phenotype in Drosophila. Ambrus AM, et al. Genetics, 2009 Sep. PMID 19546319, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables iron ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA
Inferred from Electronic Annotation
more info
  
enables stearoyl-CoA 9-desaturase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables stearoyl-CoA 9-desaturase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in unsaturated fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9747-PA
CG9747-PB
NP_001287604.1
NP_651779.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    30185423..30191252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300675.1 → NP_001287604.1  uncharacterized protein Dmel_CG9747, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287604.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VA94
    Conserved Domains (2) summary
    cd03505
    Location:135 → 376
    Delta9-FADS-like; The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide ...
    pfam00487
    Location:140 → 343
    FA_desaturase; Fatty acid desaturase

  2. NM_143522.4 → NP_651779.1  uncharacterized protein Dmel_CG9747, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651779.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VA94
    Related
    FBpp0084939
    Conserved Domains (2) summary
    cd03505
    Location:135 → 376
    Delta9-FADS-like; The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide ...
    pfam00487
    Location:140 → 343
    FA_desaturase; Fatty acid desaturase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VA94 Q9VA94

Gene LinkOut

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