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Etfb Electron transfer flavoprotein beta subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43515, updated on 9-Dec-2024

Summary

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Official Symbol
Etfbprovided by FlyBase
Official Full Name
Electron transfer flavoprotein beta subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0039697
Locus tag
Dmel_CG7834
See related
AllianceGenome:FB:FBgn0039697
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG 7834; CG7834; Dmel\CG7834; ETFB; Q0KHZ6
Summary
Predicted to enable electron transfer activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrion. Is expressed in several structures, including adult head; adult heart; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Orthologous to human ETFB (electron transfer flavoprotein subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Etfb in Genome Data Viewer
Location:
99C1-99C1; 3-99 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29801599..29802945, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25627321..25628667, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene shroud Neighboring gene R and B Neighboring gene Death related ICE-like caspase Neighboring gene uncharacterized protein Neighboring gene non-claret disjunctional Neighboring gene claret Neighboring gene Vacuolar protein sorting 16B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Katewa SD, et al. Cell Metab, 2012 Jul 3. PMID 22768842, Free PMC Article
  2. Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster. Jumbo-Lucioni P, et al. BMC Genomics, 2012 Nov 22. PMID 23171078, Free PMC Article
  3. The TreadWheel: A Novel Apparatus to Measure Genetic Variation in Response to Gently Induced Exercise for Drosophila. Mendez S, et al. PLoS One, 2016. PMID 27736996, Free PMC Article
  4. The genetic basis of adaptation to copper pollution in Drosophila melanogaster. Everman ER, et al. Front Genet, 2023. PMID 37082199, Free PMC Article
  5. DRONC coordinates cell death and compensatory proliferation. Kondo S, et al. Mol Cell Biol, 2006 Oct. PMID 16980627, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables electron transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables electron transfer activity IEA
Inferred from Electronic Annotation
more info
  
enables electron transfer activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
electron transfer flavoprotein beta subunit
Names
CG7834-PA
CG7834-PB
Etfb-PA
Etfb-PB
electron transfer flavoprotein beta-subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29801599..29802945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170428.2 → NP_733307.1  electron transfer flavoprotein beta subunit, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733307.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHZ6, Q8MR58
    Related
    FBpp0084902
    Conserved Domains (1) summary
    COG2086
    Location:3 → 249
    FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]

  2. NM_143470.2 → NP_651727.1  electron transfer flavoprotein beta subunit, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651727.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHZ6, Q8MR58
    Related
    FBpp0084901
    Conserved Domains (1) summary
    COG2086
    Location:3 → 249
    FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0KHZ6 Q0KHZ6
Q8MR58 Q8MR58

Gene LinkOut

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