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alpha-Man-Ib - alpha-Mannosidase class I b

Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in encapsulation of foreign target. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in several structures, including adult head; amnioserosa; embryonic proventriculus; embryonic/larval salivary gland; and ganglia. Human ortholog(s) of this gene implicated in Rafiq syndrome. Orthologous to human MAN1B1 (mannosidase alpha class 1B member 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa