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wdn wings down [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43398, updated on 9-Dec-2024

Summary

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Official Symbol
wdnprovided by FlyBase
Official Full Name
wings downprovided by FlyBase
Primary source
FLYBASE:FBgn0005642
Locus tag
Dmel_CG1454
See related
AllianceGenome:FB:FBgn0005642
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1454; Dmel\CG1454; pqp; sry h-l; sry-c; sry-h1; Sryc
Summary
Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including antennal primordium; embryonic/larval midgut primordium; female germline cell; ganglia; and head epidermis primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See wdn in Genome Data Viewer
Location:
98E5-98E5; 3-97 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28807983..28811337, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24633705..24637059, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene intrepid Neighboring gene Chemosensory protein A 98a Neighboring gene ncRNA Neighboring gene pre-mRNA processing factor 39 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. sry h-1, a new Drosophila melanogaster multifingered protein gene showing maternal and zygotic expression. Vincent A, et al. Mol Cell Biol, 1988 Oct. PMID 3141791, Free PMC Article
  2. The Drosophila pourquoi-pas?/wings-down zinc finger protein: oocyte nucleus localization and embryonic requirement. Ségalat L, et al. Genes Dev, 1992 Jun. PMID 1592256
  3. Dissection of the Drosophila pourquoi-pas? promoter: complex ovarian expression is driven by distinct follicle cell- and germ line-specific enhancers. Ségalat L, et al. Mech Dev, 1994 Sep. PMID 7848871
  4. Intercellular cytoplasm transport during Drosophila oogenesis. Mahajan-Miklos S, et al. Dev Biol, 1994 Oct. PMID 7958404
  5. New Drosophila Long-Term Memory Genes Revealed by Assessing Computational Function Prediction Methods. Kacsoh BZ, et al. G3 (Bethesda), 2019 Jan 9. PMID 30463884, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
wings down
Names
CG1454-PA
pourquoi-pas
serendipity cognate
serendipity-cognate
wdn-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    28807983..28811337 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057552.4 → NP_476900.1  wings down [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476900.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15619, Q9VAT4
    Related
    FBpp0084725
    Conserved Domains (4) summary
    COG1594
    Location:333 → 425
    RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]
    sd00017
    Location:360 → 380
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:358 → 380
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:372 → 395
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P15619.2 P15619

Gene LinkOut

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