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CG1894 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43378, updated on 9-Dec-2024

Summary

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Official Symbol
CG1894provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039585
Locus tag
Dmel_CG1894
See related
AllianceGenome:FB:FBgn0039585
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1894; dmHAG407; HAT
Summary
Predicted to enable chromatin binding activity; histone H4K16 acetyltransferase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in chromosome, telomeric region and euchromatin. Orthologous to human KAT8 (lysine acetyltransferase 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG1894 in Genome Data Viewer
Location:
98D2-98D2; 3-96 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28484557..28486062)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24310279..24311784)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Odorant receptor 98b Neighboring gene long non-coding RNA:CR46106 Neighboring gene beaten path VI Neighboring gene Dynein heavy chain at 89D Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pcaf modulates polyglutamine pathology in a Drosophila model of Huntington's disease. Bodai L, et al. Neurodegener Dis, 2012. PMID 21912091, Free PMC Article
  2. The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Yang XJ. Nucleic Acids Res, 2004. PMID 14960713, Free PMC Article
  3. Widespread colocalization of the Drosophila histone acetyltransferase homolog MYST5 with DREF and insulator proteins at active genes. Heseding C, et al. Chromosoma, 2017 Feb. PMID 26894919
  4. Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex. Jugder BE, et al. Immunity, 2021 Aug 10. PMID 34107298, Free PMC Article
  5. Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families. Sanjuán R, et al. Mol Biol Evol, 2001 Mar. PMID 11230534

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables histone H4K16 acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables histone acetyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of MSL complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NSL complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chromosome, telomeric region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in euchromatin IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG1894-PA
NP_651620.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    28484557..28486062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143363.3 → NP_651620.1  uncharacterized protein Dmel_CG1894 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651620.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VAV6
    Related
    FBpp0084659
    Conserved Domains (2) summary
    pfam01853
    Location:202 → 378
    MOZ_SAS; MOZ/SAS family
    cl17182
    Location:130 → 395
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VAV6 Q9VAV6

Gene LinkOut

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