U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG4815 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43360, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
CG4815provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039568
Locus tag
Dmel_CG4815
See related
AllianceGenome:FB:FBgn0039568
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4815; SP189
Summary
Predicted to enable serine-type endopeptidase activity. Involved in sexual reproduction. Located in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG4815 in Genome Data Viewer
Location:
98B7-98B7; 3-94 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27989699..27990751, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23815421..23816473, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene beta-Tubulin at 97EF Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46087 Neighboring gene long noncoding RNA: testis-specific 27 Neighboring gene trivet

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Drosophila melanogaster seminal fluid protease "seminase" regulates proteolytic and post-mating reproductive processes. LaFlamme BA, et al. PLoS Genet, 2012 Jan. PMID 22253601, Free PMC Article
  2. Molecular evolution under increasing transposable element burden in Drosophila: a speed limit on the evolutionary arms race. Castillo DM, et al. BMC Evol Biol, 2011 Sep 14. PMID 21917173, Free PMC Article
  3. Identification and function of proteolysis regulators in seminal fluid. Laflamme BA, et al. Mol Reprod Dev, 2013 Feb. PMID 23109270, Free PMC Article
  4. Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies. Nakano S, et al. PLoS Genet, 2023 Jun. PMID 37319131, Free PMC Article
  5. A Drosophila screen identifies a role for histone methylation in ER stress preconditioning. Owings KG, et al. G3 (Bethesda), 2024 Feb 7. PMID 38098286, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 
involved_in sexual reproduction HEP PubMed 
Component Evidence Code Pubs
located_in extracellular space HDA PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG4815-PA
NP_651607.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    27989699..27990751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143350.2 → NP_651607.1  uncharacterized protein Dmel_CG4815 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651607.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VAX6
    Related
    FBpp0084629
    Conserved Domains (2) summary
    pfam00089
    Location:49 → 256
    Trypsin; Trypsin
    cl21584
    Location:49 → 259
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VAX6 Q9VAX6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools