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Hmu Hemomucin [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43294, updated on 9-Dec-2024

Summary

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Official Symbol
Hmuprovided by FlyBase
Official Full Name
Hemomucinprovided by FlyBase
Primary source
FLYBASE:FBgn0015737
Locus tag
Dmel_CG3373
See related
AllianceGenome:FB:FBgn0015737
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3373; Dmel\CG3373; hmu; Rbp5; rrm5; RRM5; SPH210
Summary
Predicted to enable arylesterase activity. Predicted to be involved in biosynthetic process. Located in cell surface. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; epithelium; ganglia; and gut section. Orthologous to human APMAP (adipocyte plasma membrane associated protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Hmu in Genome Data Viewer
Location:
97F1-97F1; 3-93 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27288769..27291592)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23114491..23117314)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene martik Neighboring gene uncharacterized protein Neighboring gene bigmax Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44287 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Changes in glycosylation during Drosophila development. The influence of ecdysone on hemomucin isoforms. Theopold U, et al. Insect Biochem Mol Biol, 2001 Feb. PMID 11164341
  2. Is the surface of endoparasitic wasp eggs and larvae covered by a limited coagulation reaction? Kinuthia W, et al. J Insect Physiol, 1999 May. PMID 12770334
  3. Helix pomatia lectin, an inducer of Drosophila immune response, binds to hemomucin, a novel surface mucin. Theopold U, et al. J Biol Chem, 1996 May 31. PMID 8662683
  4. Animal and plant members of a gene family with similarity to alkaloid-synthesizing enzymes. Fabbri M, et al. Biochem Biophys Res Commun, 2000 Apr 29. PMID 10777701
  5. Peritrophic matrix proteins. Tellam RL, et al. Insect Biochem Mol Biol, 1999 Feb. PMID 10196732

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Hmu, Sr-CI/Sr-CIII, and Tehao have polymorphic sites in nearly perfect linkage disequilibrium
    Title: Linkage disequilibrium and recent selection at three immunity receptor loci in Drosophila simulans.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables arylesterase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables strictosidine synthase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endomembrane system HDA PubMed 

General protein information

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Preferred Names
hemomucin
Names
CG3373-PA
Hmu-PA
RNA-binding protein 5
NP_477159.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    27288769..27291592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057811.4 → NP_477159.1  hemomucin [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477159.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D2NUG9, Q24160, Q8MT56, Q9VB46
    UniProtKB/TrEMBL
    Q58SN2
    Related
    FBpp0084534
    Conserved Domains (2) summary
    COG3386
    Location:61 → 287
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cl22863
    Location:173 → 258
    Str_synth; Strictosidine synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q26275 Q26275
Q58SM8 Q58SM8
Q58SM9 Q58SM9
Q58SN0 Q58SN0
Q58SN1 Q58SN1
Q58SN2 Q58SN2
Q58SN3 Q58SN3
Q58SN4 Q58SN4
Q9VB46.1 Q9VB46

Gene LinkOut

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