Gm5431 predicted gene 5431 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gm5431provided by MGI
Official Full Name: predicted gene 5431provided by MGI
Primary source: MGI:MGI:3645205
See related: Ensembl:ENSMUSG00000058163 AllianceGenome:MGI:3645205
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Irgb9b8; EG432555
Summary: Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly; cellular response to interferon-beta; and innate immune response. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jan 2025]
Expression: Broad expression in large intestine adult (RPKM 1.7), mammary gland adult (RPKM 0.7) and 15 other tissues See more
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Genomic context

Location:: 11 B1.2; 11 28.87 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (48778249..48792979, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (48887422..48902152, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in autophagosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to interferon-beta	IBA Inferred from Biological aspect of Ancestor more info
involved_in innate immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein LOC432555

Names: Immunity related GTPase, B9-B8 tandem, WSB specific; novel interferon-inducible GTPase (IIGP) family member

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024230.2 → NP_001019401.2 uncharacterized protein LOC432555

Status: VALIDATED

Source sequence(s)

AK165745, AL645849

Consensus CDS

CCDS36141.2

UniProtKB/TrEMBL

A6PWD6, Q3TMS7

Related

ENSMUSP00000104833.2, ENSMUST00000109210.8

Conserved Domains (2) summary

cd04104
Location:203 → 399

p47_IIGP_like; p47 GTPase family includes IGTP, TGTP/Mg21, IRG-47, GTPI, LRG-47, and IIGP1

pfam05049
Location:169 → 541

IIGP; Interferon-inducible GTPase (IIGP)