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plpp5 phospholipid phosphatase 5 [ Danio rerio (zebrafish) ]

Gene ID: 431758, updated on 4-Jan-2025

Summary

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Official Symbol
plpp5provided by ZNC
Official Full Name
phospholipid phosphatase 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-040704-54
See related
Ensembl:ENSDARG00000057672 AllianceGenome:ZFIN:ZDB-GENE-040704-54
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc49c04; ppapdc1b; zgc:92365; wu:fc49c04
Summary
Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Orthologous to human PLPP5 (phospholipid phosphatase 5). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See plpp5 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (20527427..20537035, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (20570046..20579765, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene transforming, acidic coiled-coil containing protein 1 Neighboring gene uncharacterized LOC137496580 Neighboring gene DDHD domain containing 2 Neighboring gene nuclear receptor binding SET domain protein 3 Neighboring gene leucine zipper-EF-hand containing transmembrane protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification and expression of liver-specific genes after LPS challenge in amphioxus: the hepatic cecum as liver-like organ and "pre-hepatic" acute phase response. Wang Y, et al. Funct Integr Genomics, 2011 Mar. PMID 21052758
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phospholipid phosphatase 5
Names
phosphatidic acid phosphatase type 2 domain containing 1B
NP_001002211.1
NP_001417792.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002211.2 → NP_001002211.1  phospholipid phosphatase 5

    See identical proteins and their annotated locations for NP_001002211.1

    Status: VALIDATED

    Source sequence(s)
    BX294119
    UniProtKB/TrEMBL
    Q6GMH7
    Related
    ENSDARP00000064602.4, ENSDART00000064603.6
    Conserved Domains (1) summary
    cd03390
    Location:42 → 230
    PAP2_containing_1_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both ...

  2. NM_001430863.1 → NP_001417792.1  phospholipid phosphatase 5

    Status: VALIDATED

    Source sequence(s)
    BX294119
    UniProtKB/TrEMBL
    Q6GMH7
    Related
    ENSDARP00000116112.1, ENSDART00000135341.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    20527427..20537035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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