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E(spl)m5-HLH - Enhancer of split m5, helix-loop-helix

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; protein dimerization activity; and sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including anlage in statu nascendi; embryonic segment; epithelium; germ layer; and head epidermis primordium. Orthologous to human HES2 (hes family bHLH transcription factor 2). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to E(spl)m5-HLH

NCBI Orthologs

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Species Gene Architecture aa