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CG5913 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43132, updated on 4-Jan-2025

Summary

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Official Symbol
CG5913provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039385
Locus tag
Dmel_CG5913
See related
AllianceGenome:FB:FBgn0039385
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5913
Summary
Predicted to enable RNA binding activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of tRNA-splicing ligase complex. Is expressed in several structures, including adult head; embryonic/larval midgut; ganglia; and larval nervous system. Orthologous to several human genes including FAM98A (family with sequence similarity 98 member A) and FAM98B (family with sequence similarity 98 member B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG5913 in Genome Data Viewer
Location:
96F6-96F6; 3-89 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25893495..25895026)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21719217..21720748)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Signal peptide peptidase-like Neighboring gene Lnk Neighboring gene Sodesque Neighboring gene Multicopper oxidase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rare variants in MYH15 modify amyotrophic lateral sclerosis risk. Kim H, et al. Hum Mol Genet, 2019 Jul 15. PMID 30985904, Free PMC Article
  2. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Slack C, et al. PLoS Genet, 2010 Mar 19. PMID 20333234, Free PMC Article
  3. The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling. Xu C, et al. Cell Rep, 2019 Jan 15. PMID 30650359, Free PMC Article
  4. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
  5. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of tRNA-splicing ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5913-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    25893495..25895026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143182.4 → NP_651439.2  uncharacterized protein Dmel_CG5913 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651439.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q960C1, Q9VBK9
    Related
    FBpp0084312
    Conserved Domains (1) summary
    pfam10239
    Location:9 → 328
    DUF2465; Protein of unknown function (DUF2465)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q960C1 Q960C1
Q9VBK9 Q9VBK9

Gene LinkOut

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