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Mink Mitotic spindle and nuclear protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42982, updated on 4-Jan-2025

Summary

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Official Symbol
Minkprovided by FlyBase
Official Full Name
Mitotic spindle and nuclear proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039250
Locus tag
Dmel_CG11120
See related
AllianceGenome:FB:FBgn0039250
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11120; Dmel\CG11120; mink
Summary
Enables microtubule binding activity. Predicted to be involved in establishment of mitotic spindle localization; mitotic chromosome condensation; and mitotic cytokinesis. Located in mitotic spindle and nucleus. Is expressed in several structures, including CNS glial cell; antennal primordium; central brain primordium; ganglia; and head epidermis primordium. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Mink in Genome Data Viewer
Location:
96B8-96B9; 3-86 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24922473..24925160)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20748195..20750882)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class S Neighboring gene sudestada1 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46097 Neighboring gene Topoisomerase related function 4-2 Neighboring gene uncharacterized protein Neighboring gene Oxysterol binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition. Syred HM, et al. Mol Cell Proteomics, 2013 Nov. PMID 23893837, Free PMC Article
  2. TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster. Nakamura R, et al. Mol Cell Biol, 2008 Nov. PMID 18765642, Free PMC Article
  3. The phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin. Repton C, et al. PLoS Genet, 2022 Jun. PMID 35666772, Free PMC Article
  4. Impact of tRNA-induced proline-to-serine mistranslation on the transcriptome of Drosophila melanogaster. Isaacson JR, et al. G3 (Bethesda), 2024 Sep 4. PMID 38989890, Free PMC Article
  5. Single-cell sequencing of tumor-associated macrophages in a Drosophila model. Khalili D, et al. Front Immunol, 2023. PMID 37795097, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in establishment of mitotic spindle localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in establishment of mitotic spindle localization IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic chromosome condensation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitotic spindle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in spindle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitotic spindle and nuclear protein
Names
CG11120-PA
Mink-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24922473..24925160
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143055.4 → NP_651312.2  mitotic spindle and nuclear protein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651312.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MT75, Q9VC08
    Related
    FBpp0084092
    Conserved Domains (1) summary
    pfam16006
    Location:557 → 704
    NUSAP; Nucleolar and spindle-associated protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VC08 Q9VC08

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