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Srg1 Sting-regulated gene 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42969, updated on 9-Dec-2024

Summary

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Official Symbol
Srg1provided by FlyBase
Official Full Name
Sting-regulated gene 1provided by FlyBase
Primary source
FLYBASE:FBgn0039239
Locus tag
Dmel_CG13641
See related
AllianceGenome:FB:FBgn0039239
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13641; Dmel\CG13641; srg1
Summary
Involved in defense response to virus. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Srg1 in Genome Data Viewer
Location:
96B1-96B1; 3-86 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24864191..24864732, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20689913..20690454, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Elastin-like Neighboring gene Cyclin B3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila. Slavik KM, et al. Nature, 2021 Sep. PMID 34261127, Free PMC Article
  2. Dietary Supplementation of Aspirin Promotes Drosophila Defense against Viral Infection. Kong F, et al. Molecules, 2023 Jul 9. PMID 37513173, Free PMC Article
  3. Two cGAS-like receptors induce antiviral immunity in Drosophila. Holleufer A, et al. Nature, 2021 Sep. PMID 34261128
  4. 2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in Drosophila. Cai H, et al. Sci Signal, 2020 Dec 1. PMID 33262294
  5. The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila. Goto A, et al. Immunity, 2018 Aug 21. PMID 30119996, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in defense response to virus IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
Sting-regulated gene 1
Names
CG13641-PA
Srg1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24864191..24864732 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143045.3 → NP_651302.1  Sting-regulated gene 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651302.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VC22
    Related
    FBpp0084104
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VC22 Q9VC22

Gene LinkOut

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