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nAChRalpha2 - nicotinic Acetylcholine Receptor alpha2

Contributes to acetylcholine receptor activity and acetylcholine-gated monoatomic cation-selective channel activity. Involved in cholinergic synaptic transmission and monoatomic cation transmembrane transport. Part of acetylcholine-gated channel complex. Is expressed in several structures, including adult head; dorsal ectoderm; dorsal ectoderm anlage; dorsal epidermis primordium; and ganglia. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; autosomal dominant nocturnal frontal lobe epilepsy 1; congenital myasthenic syndrome (multiple); and lung cancer (multiple). Orthologous to several human genes including CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to nAChRalpha2

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Species Gene Architecture aa