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BRWD3 - BRWD3

Involved in several processes, including autophagic cell death; larval midgut cell programmed cell death; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to be active in nucleus. Is expressed in adult heart; embryonic/larval salivary gland; and spermatozoon. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 93 and primary ciliary dyskinesia. Orthologous to several human genes including BRWD3 (bromodomain and WD repeat domain containing 3) and PHIP (pleckstrin homology domain interacting protein). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa