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CG10694 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42855, updated on 4-Jan-2025

Summary

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Official Symbol
CG10694provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039147
Locus tag
Dmel_CG10694
See related
AllianceGenome:FB:FBgn0039147
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10694
Summary
Predicted to enable polyubiquitin modification-dependent protein binding activity; proteasome binding activity; and ubiquitin binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol and nucleoplasm. Orthologous to human RAD23B (RAD23 homolog B, nucleotide excision repair protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG10694 in Genome Data Viewer
Location:
95E1-95E1; 3-83 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24107391..24108358)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19933113..19934080)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Structural maintenance of chromosomes 1 Neighboring gene eukaryotic translation initiation factor 4E homologous protein Neighboring gene Syntaxin 1A Neighboring gene transfer RNA:Leucine-TAA 2-1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. FoxO suppresses endoplasmic reticulum stress to inhibit growth of Tsc1-deficient tissues under nutrient restriction. Gupta A, et al. Elife, 2020 Jun 11. PMID 32525804, Free PMC Article
  2. The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster. Svetec N, et al. PLoS Genet, 2016 Mar. PMID 26950216, Free PMC Article
  3. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395, Free PMC Article
  4. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article
  5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables proteasome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10694-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24107391..24108358
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142955.3 → NP_651212.1  uncharacterized protein Dmel_CG10694 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651212.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VCD5
    Related
    FBpp0083927
    Conserved Domains (5) summary
    cd14280
    Location:110 → 148
    UBA1_Rad23_like; UBA1 domain of Rad23 proteins found in eukaryotes
    cd14281
    Location:245 → 282
    UBA2_Rad23_like; UBA2 domain of Rad23 proteins found in eukaryotes
    TIGR00601
    Location:1 → 284
    rad23; UV excision repair protein Rad23
    pfam09280
    Location:172 → 227
    XPC-binding; XPC-binding domain
    cl00155
    Location:1 → 76
    UBQ; Ubiquitin-like proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VCD5 Q9VCD5

Gene LinkOut

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