Nup98-96 - Nucleoporin 98-96kD

Enables promoter-enhancer loop anchoring activity and promoter-specific chromatin binding activity. Involved in several processes, including heat shock-mediated polytene chromosome puffing; nucleocytoplasmic transport; and positive regulation of macromolecule biosynthetic process. Located in chromosome; cytoplasm; and nucleus. Part of nuclear pore. Is expressed in adult head; cyst progenitor cell; and male germline stem cell. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Orthologous to human NUP98 (nucleoporin 98 and 96 precursor). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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