lmd - lame duck
Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including myoblast fusion; positive regulation of transcription by RNA polymerase II; and somatic muscle development. Located in cytosol and nucleus. Is expressed in several structures, including dorsal pharyngeal muscle primordium; fusion competent cell; larval somatic muscle cell; mesoderm; and visceral muscle primordium. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in neonatal diabetes mellitus with congenital hypothyroidism. Orthologous to human GLIS1 (GLIS family zinc finger 1) and GLIS3 (GLIS family zinc finger 3). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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