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CG4907 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42686, updated on 4-Jan-2025

Summary

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Official Symbol
CG4907provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039010
Locus tag
Dmel_CG4907
See related
AllianceGenome:FB:FBgn0039010
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4907
Summary
Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 1. Orthologous to human PIGN (phosphatidylinositol glycan anchor biosynthesis class N). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG4907 in Genome Data Viewer
Location:
94C2-94C2; 3-76 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22707786..22710762, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18533508..18536484, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Crustacean cardioactive peptide Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene winged eye Neighboring gene Iron regulatory protein 1A Neighboring gene antisense RNA:CR45648

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Involvement of winged eye encoding a chromatin-associated bromo-adjacent homology domain protein in disc specification. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2005 Nov 1. PMID 16247005, Free PMC Article
  2. The RNA export factor, Nxt1, is required for tissue specific transcriptional regulation. Caporilli S, et al. PLoS Genet, 2013 Jun. PMID 23754955, Free PMC Article
  3. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article
  4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
  5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables mannose-ethanolamine phosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mannose-ethanolamine phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4907-PA
NP_651086.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    22707786..22710762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142829.3 → NP_651086.1  uncharacterized protein Dmel_CG4907 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651086.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IHE6, Q9VCV7
    Related
    FBpp0083723
    Conserved Domains (2) summary
    pfam04987
    Location:413 → 858
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:42 → 327
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IHE6 Q8IHE6
Q8T3S3 Q8T3S3
Q9VCV7 Q9VCV7

Gene LinkOut

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