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Polr1H RNA polymerase I subunit H [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42563, updated on 4-Jan-2025

Summary

Official Symbol
Polr1Hprovided by FlyBase
Official Full Name
RNA polymerase I subunit Hprovided by FlyBase
Primary source
FLYBASE:FBgn0038903
Locus tag
Dmel_CG13418
See related
AllianceGenome:FB:FBgn0038903
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13418; Dmel\CG13418; RPA12; RpI12
Summary
Predicted to enable DNA-directed 5'-3' RNA polymerase activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in termination of RNA polymerase I transcription. Predicted to be part of RNA polymerase I complex. Orthologous to human POLR1H (RNA polymerase I subunit H). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Polr1H in Genome Data Viewer
Location:
93F9-93F9; 3-73 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21777203..21777847, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17602925..17603569, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene metabotropic GABA-B receptor subtype 2 Neighboring gene Bursicon Neighboring gene uncharacterized protein Neighboring gene torso-like Neighboring gene CASK regulatory gene Neighboring gene CASK

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase I activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase I activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in termination of RNA polymerase I transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transcription by RNA polymerase I ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RNA polymerase I complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
RNA polymerase I subunit H
Names
CG13418-PA
Polr1H-PA
RpI12
NP_524439.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    21777203..21777847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079715.3NP_524439.1  RNA polymerase I subunit H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524439.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VD81
    Related
    FBpp0083564
    Conserved Domains (2) summary
    COG1594
    Location:10119
    RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]
    cd10507
    Location:73119
    Zn-ribbon_RPA12; C-terminal zinc ribbon domain of RPA12 subunit of RNA polymerase I