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SNF4Agamma - SNF4/AMP-activated protein kinase gamma subunit

Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Involved in several processes, including behavioral response to starvation; cholesterol homeostasis; and sequestering of triglyceride. Located in cytoplasm and nucleus. Is expressed in several structures, including adult head; adult ventral nerve cord; anterior endoderm; embryonic/larval midgut primordium; and larval midline neurons. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; glycogen storage disease; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Orthologous to several human genes including PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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Species Gene Architecture aa