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rtet tetracycline resistance [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42500, updated on 9-Dec-2024

Summary

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Official Symbol
rtetprovided by FlyBase
Official Full Name
tetracycline resistanceprovided by FlyBase
Primary source
FLYBASE:FBgn0028468
Locus tag
Dmel_CG5760
See related
AllianceGenome:FB:FBgn0028468
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0119857.1; BcDNA:LD28419; CG5760; Dmel\CG5760; Drtet; l(3)07086
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in brush border membrane. Is expressed in embryonic anal pad; embryonic foregut; embryonic head epidermis; embryonic hindgut; and organism. Orthologous to human MFSD10 (major facilitator superfamily domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See rtet in Genome Data Viewer
Location:
93B12-93B12; 3-70 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21108446..21110834)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16934168..16936556)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46045 Neighboring gene TBC1 domain family member 22 Neighboring gene Secretory 15 Neighboring gene Rab11 Neighboring gene peter pan Neighboring gene Bride of doubletime

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rab11 maintains connections between germline stem cells and niche cells in the Drosophila ovary. Bogard N, et al. Development, 2007 Oct. PMID 17715175
  2. Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Mehta SQ, et al. Neuron, 2005 Apr 21. PMID 15848801
  3. Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster. Ceder MM, et al. Front Cell Dev Biol, 2020. PMID 32733888, Free PMC Article
  4. Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression. Perland E, et al. Open Biol, 2017 Sep. PMID 28878041, Free PMC Article
  5. Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations. Perrimon N, et al. Genetics, 1996 Dec. PMID 8978055, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in brush border membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
tetracycline resistance
Names
CG5760-PA
rtet-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    21108446..21110834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079705.3 → NP_524429.1  tetracycline resistance [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524429.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V395
    Related
    FBpp0083412
    Conserved Domains (2) summary
    cd06174
    Location:105 → 466
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:108 → 442
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V395 Q9V395

Gene LinkOut

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