AnxB9 Annexin B9 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: AnxB9provided by FlyBase
Official Full Name: Annexin B9provided by FlyBase
Primary source: FLYBASE:FBgn0000083
Locus tag: Dmel_CG5730
See related: AllianceGenome:FB:FBgn0000083
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Ann; AnnB9; annexin; AnnIX; Anx B9; ANXB9; CG5730; Dmel\CG5730
Summary: Enables spectrin binding activity. Involved in endosome transport via multivesicular body sorting pathway; maintenance of cell polarity; and wing disc dorsal/ventral pattern formation. Located in cell cortex and endomembrane system. Is expressed in adult head and adult heart. Orthologous to several human genes including ANXA7 (annexin A7). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (21065241..21070917)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (16890963..16896639)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Cytoplasmic capes are nuclear envelope intrusions that are enriched in endosomal proteins and depend upon betaH-spectrin and Annexin B9.
Title: Cytoplasmic capes are nuclear envelope intrusions that are enriched in endosomal proteins and depend upon βH-spectrin and Annexin B9.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables calcium-dependent phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium-dependent phospholipid binding	IEA Inferred from Electronic Annotation more info
enables calcium-dependent phospholipid binding	ISS Inferred from Sequence or Structural Similarity more info
enables phosphatidylserine binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables spectrin binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in endosome transport via multivesicular body sorting pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in endosome transport via multivesicular body sorting pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maintenance of cell polarity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in wing disc dorsal/ventral pattern formation	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cell cortex	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in endomembrane system	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: AnxB9-PA; AnxB9-PB; AnxB9-PC; AnxB9-PD; AnxB9-PE; AnxB9-PF; CG5730-PA; CG5730-PB; CG5730-PC; CG5730-PD; CG5730-PE; CG5730-PF; annexin; annexin B9a; annexin IX