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CG5412 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42434, updated on 9-Dec-2024

Summary

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Official Symbol
CG5412provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038806
Locus tag
Dmel_CG5412
See related
AllianceGenome:FB:FBgn0038806
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5412
Summary
Enables serine hydrolase activity. Predicted to be active in cytoplasm and nucleus. Orthologous to human OVCA2 (OVCA2 serine hydrolase domain containing). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG5412 in Genome Data Viewer
Location:
92F2-92F2; 3-69 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20577053..20578131)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16402775..16403853)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene mitochondrial transcription factor A Neighboring gene Elongin B Neighboring gene Signal recognition particle 14 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity. Spresser CR, et al. J Genet, 2008 Aug. PMID 18776638
  2. Single-cell RNA sequencing identifies eggplant as a regulator of germ cell development in Drosophila. Sun Z, et al. EMBO Rep, 2023 Oct 9. PMID 37603128, Free PMC Article
  3. Genome-wide measurement of spatial expression in patterning mutants of Drosophila melanogaster. Combs PA, et al. F1000Res, 2017. PMID 28299188, Free PMC Article
  4. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
  5. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lysophospholipase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables serine hydrolase activity HDA PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5412-PA
NP_650895.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20577053..20578131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142638.3 → NP_650895.1  uncharacterized protein Dmel_CG5412 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650895.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VDL1
    Related
    FBpp0083317
    Conserved Domains (2) summary
    COG0596
    Location:177 → 244
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    pfam03959
    Location:28 → 230
    FSH1; Serine hydrolase (FSH1)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VDL1.1 Q9VDL1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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