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CG4360 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42413, updated on 9-Dec-2024

Summary

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Official Symbol
CG4360provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038787
Locus tag
Dmel_CG4360
See related
AllianceGenome:FB:FBgn0038787
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4360
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human ZNF355P (zinc finger protein 355, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG4360 in Genome Data Viewer
Location:
92E2-92E3; 3-68 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20324274..20328003, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16149996..16153725, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Oxysterol-binding protein-related protein 8 Neighboring gene antisense RNA:CR45800 Neighboring gene Sirtuin 2 Neighboring gene Ionotropic receptor 92a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Global analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants. Enuameh MS, et al. Genome Res, 2013 Jun. PMID 23471540, Free PMC Article
  2. Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature. Zane F, et al. Aging Cell, 2023 Nov. PMID 37822253, Free PMC Article
  3. The β-alanine transporter BalaT is required for visual neurotransmission in Drosophila. Han Y, et al. Elife, 2017 Aug 14. PMID 28806173, Free PMC Article
  4. Integrating motif, DNA accessibility and gene expression data to build regulatory maps in an organism. Blatti C, et al. Nucleic Acids Res, 2015 Apr 30. PMID 25791631, Free PMC Article
  5. Pervasive variation of transcription factor orthologs contributes to regulatory network evolution. Nadimpalli S, et al. PLoS Genet, 2015 Mar. PMID 25748510, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4360-PA
CG4360-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20324274..20328003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142622.3 → NP_650879.1  uncharacterized protein Dmel_CG4360, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650879.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDN4
    Related
    FBpp0083307
    Conserved Domains (3) summary
    sd00017
    Location:144 → 164
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:157 → 181
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:287 → 363
    zf-C2H2_8; C2H2-type zinc ribbon

  2. NM_001104374.3 → NP_001097844.1  uncharacterized protein Dmel_CG4360, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097844.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q29R02
    Conserved Domains (3) summary
    sd00017
    Location:144 → 164
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:157 → 181
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:287 → 363
    zf-C2H2_8; C2H2-type zinc ribbon
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29R02 Q29R02
Q9VDN4 Q9VDN4

Gene LinkOut

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