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CG4836 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42387, updated on 9-Dec-2024

Summary

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Official Symbol
CG4836provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0270925
Locus tag
Dmel_CG4836
See related
AllianceGenome:FB:FBgn0270925
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.105; anon-WO0140519.33; bs15h04.y1; bs36e10.y1; Dmel\CG4836; DM_7300579; SODH-1; Srd
Summary
Predicted to enable L-iditol 2-dehydrogenase (NAD+) activity. Predicted to be involved in sorbitol catabolic process. Is expressed in adult head and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG4836 in Genome Data Viewer
Location:
92C1-92C1; 3-67 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20013872..20018248)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15839594..15843970)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Mediator complex subunit 25 Neighboring gene uncharacterized protein Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class L Neighboring gene phagocyte signaling impaired

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Do candidate genes mediating conspecific sperm precedence affect sperm competitive ability within species? A test case in Drosophila. Civetta A, et al. G3 (Bethesda), 2014 Jul 16. PMID 25031180, Free PMC Article
  2. Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster. Huylmans AK, et al. G3 (Bethesda), 2014 Sep 22. PMID 25246242, Free PMC Article
  3. Loss of Drosophila Clueless differentially affects the mitochondrial proteome compared to loss of Sod2 and Pink1. Sen A, et al. Front Physiol, 2022. PMID 36388112, Free PMC Article
  4. Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Avidor-Reiss T, et al. Cell, 2004 May 14. PMID 15137945
  5. Conserved properties of Drosophila and human spermatozoal mRNA repertoires. Fischer BE, et al. Proc Biol Sci, 2012 Jul 7. PMID 22378807, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables L-iditol 2-dehydrogenase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in sorbitol catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4836-PA
CG4836-PB
CG4836-PC
CG4836-PD
CG4836-PE
L-iditol 2-dehydrogenase
sorbitol dehydrogenase
NP_001138084.1
NP_001138085.1
NP_650856.2
NP_732476.2
NP_732477.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20013872..20018248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142599.3 → NP_650856.2  uncharacterized protein Dmel_CG4836, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650856.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDQ9
    Related
    FBpp0083237
    Conserved Domains (2) summary
    COG1063
    Location:886 → 1210
    Tdh; Threonine dehydrogenase or related Zn-dependent dehydrogenase [Amino acid transport and metabolism, General function prediction only]
    cl16912
    Location:881 → 1211
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

  2. NM_169883.2 → NP_732477.2  uncharacterized protein Dmel_CG4836, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732477.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    E0R969, Q8IN61, Q8MRL0
    Related
    FBpp0083235

  3. NM_169882.2 → NP_732476.2  uncharacterized protein Dmel_CG4836, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732476.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IN62
    Related
    FBpp0083236
    Conserved Domains (2) summary
    COG1063
    Location:883 → 1207
    Tdh; Threonine dehydrogenase or related Zn-dependent dehydrogenase [Amino acid transport and metabolism, General function prediction only]
    cl16912
    Location:878 → 1208
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

  4. NM_001144613.2 → NP_001138085.1  uncharacterized protein Dmel_CG4836, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138085.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0M7
    Conserved Domains (2) summary
    COG1063
    Location:893 → 1217
    Tdh; Threonine dehydrogenase or related Zn-dependent dehydrogenase [Amino acid transport and metabolism, General function prediction only]
    cl16912
    Location:888 → 1218
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

  5. NM_001144612.2 → NP_001138084.1  uncharacterized protein Dmel_CG4836, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138084.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0M8, E0R969
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7Z0M7 B7Z0M7
B7Z0M8 B7Z0M8
Q8IN62 Q8IN62
Q8MRL0 Q8MRL0
Q9VDQ9 Q9VDQ9

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