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CG31213 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42382, updated on 9-Dec-2024

Summary

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Official Symbol
CG31213provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051213
Locus tag
Dmel_CG31213
See related
AllianceGenome:FB:FBgn0051213
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11460; CG4794; DmCG31213; Dmel\CG31213
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Orthologous to human ABCA13 (ATP binding cassette subfamily A member 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG31213 in Genome Data Viewer
Location:
92C1-92C1; 3-67 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19972898..19979569)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15798620..15805291)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Heparan sulfate 6-O-sulfotransferase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Mediator complex subunit 25 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes. Moulton MJ, et al. Proc Natl Acad Sci U S A, 2021 Dec 28. PMID 34949639, Free PMC Article
  2. ATP-Binding Cassette (ABC) Transporter Genes Involved in Pyrethroid Resistance in the Malaria Vector Anopheles sinensis: Genome-Wide Identification, Characteristics, Phylogenetics, and Expression Profile. He Q, et al. Int J Mol Sci, 2019 Mar 20. PMID 30897799, Free PMC Article
  3. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Ren Q, et al. Nucleic Acids Res, 2007 Jan. PMID 17135193, Free PMC Article
  4. The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance. Dermauw W, et al. Insect Biochem Mol Biol, 2014 Feb. PMID 24291285
  5. The human ATP-binding cassette (ABC) transporter superfamily. Dean M, et al. Genome Res, 2001 Jul. PMID 11435397

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables lipid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in lipid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31213-PB
CG31213-PC
NP_001262752.1
NP_732473.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19972898..19979569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275823.1 → NP_001262752.1  uncharacterized protein Dmel_CG31213, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262752.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDR4
    Conserved Domains (4) summary
    TIGR01188
    Location:498 → 796
    drrA; daunorubicin resistance ABC transporter ATP-binding subunit
    cd03263
    Location:491 → 708
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:1391 → 1672
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    pfam12698
    Location:1132 → 1285
    ABC2_membrane_3; ABC-2 family transporter protein

  2. NM_169881.2 → NP_732473.2  uncharacterized protein Dmel_CG31213, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732473.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDR4
    Conserved Domains (4) summary
    TIGR01188
    Location:498 → 796
    drrA; daunorubicin resistance ABC transporter ATP-binding subunit
    cd03263
    Location:491 → 708
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:1391 → 1672
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    pfam12698
    Location:1132 → 1285
    ABC2_membrane_3; ABC-2 family transporter protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VDR4 Q9VDR4

Gene LinkOut

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