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CG42613 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42269, updated on 9-Dec-2024

Summary

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Official Symbol
CG42613provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0261262
Locus tag
Dmel_CG42613
See related
AllianceGenome:FB:FBgn0261262
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14289; CG31149; CG31222; CG5449; CT17110; CT33918; dLev-10; Dmel\CG42613; tld-like
Old locus tag
Dmel_CG31149; Dmel_CG31222
Summary
Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG42613 in Genome Data Viewer
Location:
91D5-91E1; 3-65 cM
Exon count:
23
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18929196..18978088)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14754918..14803810)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Xrp1 Neighboring gene Mitochondrial pyruvate carrier Neighboring gene uncharacterized protein Neighboring gene Smu1 spliceosomal factor Neighboring gene eucalyptus Neighboring gene deoxyribonucleoside kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Xrp1 genetically interacts with the ALS-associated FUS orthologue caz and mediates its toxicity. Mallik M, et al. J Cell Biol, 2018 Nov 5. PMID 30209068, Free PMC Article
  2. t-GRASP, a targeted GRASP for assessing neuronal connectivity. Shearin HK, et al. J Neurosci Methods, 2018 Aug 1. PMID 29792886, Free PMC Article
  3. A Regulatory Response to Ribosomal Protein Mutations Controls Translation, Growth, and Cell Competition. Lee CH, et al. Dev Cell, 2018 Aug 20. PMID 30078730, Free PMC Article
  4. Effect of spaceflight on the circadian rhythm, lifespan and gene expression of Drosophila melanogaster. Ma L, et al. PLoS One, 2015. PMID 25798821, Free PMC Article
  5. Sequoia, a tramtrack-related zinc finger protein, functions as a pan-neural regulator for dendrite and axon morphogenesis in Drosophila. Brenman JE, et al. Dev Cell, 2001 Nov. PMID 11709187

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG42613-PE
CG42613-PF
CG42613-PG
CG42613-PH
CG42613-PI

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    18929196..18978088
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001260256.1 → NP_001247185.1  uncharacterized protein Dmel_CG42613, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247185.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K760
    Conserved Domains (2) summary
    cd00041
    Location:421 → 541
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00112
    Location:987 → 1022
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

  2. NM_001414099.1 → NP_001401046.1  uncharacterized protein Dmel_CG42613, isoform I [Drosophila melanogaster]

    Status: REVIEWED

  3. NM_169844.4 → NP_732390.3  uncharacterized protein Dmel_CG42613, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732390.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE20
    Conserved Domains (2) summary
    cd00041
    Location:388 → 508
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00112
    Location:954 → 989
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

  4. NM_001260258.1 → NP_001247187.1  uncharacterized protein Dmel_CG42613, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247187.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6C8
    Conserved Domains (2) summary
    cd00041
    Location:388 → 508
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00112
    Location:954 → 989
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

  5. NM_001260257.2 → NP_001247186.1  uncharacterized protein Dmel_CG42613, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247186.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K686, D0IQI1
    Conserved Domains (3) summary
    cd00041
    Location:78 → 198
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00112
    Location:644 → 679
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl00049
    Location:17 → 61
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K686 A0A0B4K686
A0A0B4K6C8 A0A0B4K6C8
A0A0B4K760 A0A0B4K760
Q961I3 Q961I3
Q9VE20 Q9VE20

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