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Sgsh - N-sulfoglucosamine sulfohydrolase

Predicted to enable N-sulfoglucosamine sulfohydrolase activity. Predicted to be involved in glycosaminoglycan catabolic process and heparan sulfate proteoglycan catabolic process. Is expressed in several structures, including antennal primordium; anterior-posterior subdivision of organism; cuboidal/columnar epithelium; head epidermis primordium; and sense organ. Used to study mucopolysaccharidosis type IIIA. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIIA. Orthologous to human SGSH (N-sulfoglucosamine sulfohydrolase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa