Mekk1 - Mekk1
Enables MAP kinase kinase kinase activity and mitogen-activated protein kinase kinase binding activity. Involved in several processes, including cellular hyperosmotic salinity response; engulfment of apoptotic cell; and intracellular signal transduction. Predicted to be located in cytoplasm. Is expressed in adult brain. Orthologous to human MAP3K4 (mitogen-activated protein kinase kinase kinase 4). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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